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Apigenin exhibits anti-inflammatory effects in LPS-stimulated BV2 microglia through activating GSK3β/Nrf2 signaling pathway

We evaluated the anti-inflammatory effects of apigenin in this study using the Lipopolysaccharide (LPS)-stimulated BV2 microglia. Methods: BV2 cells were treated with apigenin for 1 h and then treated with LPS. The inflammatory cytokine producti

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Apigenin Exerts Anti-inflammatory Effects in an Experimental Model of Acute Pancreatitis by Down-regulating TNF-α.

Apigenin Exerts Anti-inflammatory Effects in an Experimental Model of Acute Pancreatitis by Down-regulating TNF-α. Charalabopoulos A (1) (2), Davakis S (3) (4), Lambropoulou M (5), Papalois A (2), Simopoulos C (6), Tsaroucha A (6).

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Intestinal anti-inflammatory activity of apigenin K in two rat colitis models induced by trinitrobenzenesulfonic acid and dextran sulphate sodium

In conclusion, apigenin K is found to have anti-inflammatory effects in two preclinical models of inflammatory bowel disease.

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Anti-inflammatory mechanisms of apigenin: inhibition of cyclooxygenase-2 expression, adhesion of monocytes to human umbilical vein endothelial

Taken together, these results suggest that apigenin has significant anti-inflammatory activity that involves blocking NO-mediated COX-2 expression and monocyte adherence. These results further suggest that apigenin may be useful for therapeutic

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Anti-inflammatory activity of structurally related flavonoids, Apigenin, Luteolin and Fisetin

Anti-inflammatory activity of structurally related flavonoids, Apigenin, Luteolin and Fisetin Flavonoids are widely distributed in many fruits and plants, and it has been shown that most flavonoids have anti-inflammatory activity; however, the

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Anti-Inflammatory and Neuroprotective Effect of Apigenin: Studies in the GFAP-IL6 Mouse Model of Chronic Neuroinflammation – ScienceDirect

1/7/2017 · Apigenin is a potent anti-inflammatory and neuroprotective drug and can be potentially used for neurodegenerative diseases such as AD.

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Apigenin and cancer chemoprevention: progress, potential and promise (review)

Apigenin has been shown to possess remarkable anti-inflammatory, antioxidant and anti-carcinogenic properties. In the last few years, significant progress has been made in studying the biological effects of apigenin at cellular and molecular

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Attenuation of oxidative damage and inflammatory responses by apigenin given to mice after irradiation

We determined the in vivo efficacy of apigenin, as an anti-oxidant and anti-inflammatory agent, given to mice after irradiation. Various concentrations of apigenin (0, 10, 20, and 40mg/kg body weight) were administered to mice by a single

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Apigenin – an overview | ScienceDirect Topics

Apigenin (4′, 5, 7-trihydroxyflavone) is a flavone under the category of natural flavonoid that is abundantly present in common fruits, vegetables, nuts, onions, oranges, and tea. Apigenin has various beneficial health effects such as

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Anti-inflammatory activity of structurally related flavonoids, Apigenin, Luteolin and Fisetin – ScienceDirect

1/9/2011 · ► Three flavonoids, Apigenin, Luteolin and Fisetin have related structures. ► Apigenin and Luteolin exhibit anti-inflammatory activity by inhibiting JNK and ERK. ► Fisetin fails to inhibit JNK, ERK and inflammation.

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Investigation of the anti-inflammatory and antioxidant activities of luteolin, kaempferol, apigenin and quercetin – ScienceDirect

1/3/2021 · Compared with the test results, quercetin is a perfect anti-inflammatory and antioxidant agent that has potential as an adjuvant treatment for inflammatory diseases and oxidative stress.

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Effects of C-glycosylation on anti-diabetic, anti-Alzheimer’s disease and anti-inflammatory potential of apigenin – ScienceDirect

1/2/2014 · Vitexin and isovitexin, naturally occurring C -glycosylated derivatives of apigenin, have been known to possess potent anti-diabetic, anti-Alzheimer’s disease (anti-AD), and anti-inflammatory activities.

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Investigation of oxidant/antioxidant and anti‐inflammatory effects of apigenin on apoptosis in sepsis‐induced rat lung – Cicek – – Journal of

18/2/2021 · Apigenin treatment reduces sepsis‐induced lung injury. Apigenin has antioxidant and anti‐inflammatory properties. Apigenin inhibits the active caspase‐3 pathway and proapoptotic Bax protein.

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Anti-Inflammatory Effects of Apigenin in Lipopolysaccharide-Induced Inflammatory in Acute Lung Injury by Suppressing COX-2 and NF-kB Pathway

24/6/2014 · This study aims to evaluate the possible mechanisms responsible for the anti-inflammatory effects of apigenin lipopolysaccharide (LPS)-induced inflammatory in acute lung injury. In this study, the anti-inflammatory effects of apigenin on lipopol

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Intestinal anti-inflammatory activity of apigenin K in two rat colitis models induced by trinitrobenzenesulfonic acid and dextran sulphate sodium

The aim of the present study was to test the intestinal anti-inflammatory activity of apigenin K, a soluble form of apigenin, in two models of rat colitis, namely the trinitrobenzenesulfonic acid (TNBS) model and the dextran sulphate sodium

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