pharmacokinetics of baicalin

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[Advance in studies on pharmacokinetics of baicalin]

It has significant pharmacological effects such as antimicrobial activity, anti-inflammatory and antioxidation. Baicalin is one of its main effective components. However, baicalin's low bioavailability has restricted its clinical

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Pharmacokinetics of sodium baicalin following intravenous and intramuscular administration to piglets

The purpose of this study was to determine the pharmacokinetics of baicalin after intravenous and intramuscular administration of sodium baicalin at 50 mg/kg to piglets. Plasma baicalin levels were determined by high-performance liquid

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Pharmacokinetics and Bioavailability Enhancement of Baicalin: A Review | SpringerLink

12/9/2018 · The pharmacokinetics of baicalin mainly involve gastrointestinal hydrolysis, enterohepatic recycling, carrier-mediated transport, multiple metabolism pathways, and excretion in bile and urine. Co-administration of baicalin with other herbs/drugs

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Comparative pharmacokinetics of a marker compound, baicalin in KOB extract after oral administration to normal and allergic-induced rats.

Comparative pharmacokinetics of a marker compound, baicalin in KOB extract after oral administration to normal and allergic-induced rats. Baek JS(1), Hwang CJ, Jung HW, Park YK, Kim YH, Kang JS, Cho CW.

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Pharmacokinetics of sodium baicalin following intravenous and intramuscular administration to piglets – Liu – 2019 – Journal of Veterinary

2/8/2019 · The purpose of this study was to determine the pharmacokinetics of baicalin after intravenous and intramuscular administration of sodium baicalin at 50 mg/kg to piglets. Plasma baicalin levels were determined by high‐performance liquid

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Comparison of metabolic pharmacokinetics of baicalin and baicalein in rats – PubMed

3/2/2021 · Baicalin and baicalein, a flavone glucuronide and its aglycone, are bioactive constituents of Scutellariae Radix with various beneficial activities. We have characterized and compared the metabolic pharmacokinetics of baicalin and baicalein in

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[Effect of baicalin on pharmacokinetics of chlorogenic acid in rabbits].

1. Zhongguo Zhong Yao Za Zhi. 2010 Dec;35(24):3291-3. [Effect of baicalin on pharmacokinetics of chlorogenic acid in rabbits]. [Article in Chinese] Li Z(1), Ni J, Fang G, Gao Y, Wei J. Author information: (1)School of Chinese Materia Medica,

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The effect of herbal medicine baicalin on pharmacokinetics of rosuvastatin, substrate of organic anion-transporting polypeptide 1B1

Rosuvastatin (20 mg orally) pharmacokinetics after coadministration of placebo and 50-mg baicalin tablets (three times daily orally for 14 days) were measured for up to 72 h by liquid chromatography-mass spectrometry in a two-phase randomized

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Pharmacokinetics of baicalein, baicalin and wogonin after oral administration of a standardized extract ofScutellaria baicalensis, PF-2405 in rats

The pharmacokinetics of active components such as baicalein, wogonin and oroxylin A were evaluated after oral administration of a purified extract of Scutellaria baicalensis GEORGI (PF-2405) containing the high contents of baicalein, wogonin and

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Comparison of metabolic pharmacokinetics of baicalin and baicalein in rats – Lai – 2003 – Journal of Pharmacy and Pharmacology – Wiley Online Library

18/2/2010 · We have characterized and compared the metabolic pharmacokinetics of baicalin and baicalein in rats. Baicalein was administered intravenously and orally to rats, and baicalin was orally administered. An HPLC method was used to determine the

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Comparison of metabolic pharmacokinetics of baicalin and baicalein in rats | Journal of Pharmacy and Pharmacology | Oxford Academic

18/2/2010 · We have characterized and compared the metabolic pharmacokinetics of baicalin and baicalein in rats. Baicalein was administered intravenously and orally to rats, and baicalin was orally administered. An HPLC method was used to determine the

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Frontiers | Regulatory Mechanisms of Baicalin in Cardiovascular Diseases: A Review | Pharmacology

2/11/2020 · Pharmacokinetics of Baicalin Based on some advanced detection methods, pharmacokinetic investigations involving baicalin have been broadly carried out in the past few years.

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Role of metabolism by intestinal microbiota in pharmacokinetics of oral baicalin.

In this study, the effects of intestinal microbiota on the pharmacokinetics of baicalin were investigated in normal and antibiotic-pretreated rats following p.o. administration of 100 mg/kg baicalin by using liquid chromatography/ion trap mass

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Pharmacokinetics, pharmacodynamics and toxicity of Baicalin liposome on cerebral ischemia reperfusion injury rats via intranasal administration

Pharmacokinetics, pharmacodynamics and toxicity of Baicalin liposome on cerebral ischemia reperfusion injury rats via intranasal administration Baicalin (BA) is a major active component from the traditional Chinese medicine, which has been

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Role of metabolism by intestinal microbiota in pharmacokinetics of oral baicalin | SpringerLink

18/6/2013 · Prior to our study of the effects of intestinal microbiota on the oral pharmacokinetics of baicalin, baicalin and its metabolites produced were characterized by LC/MS/MS analyses. Baicalin, metabolites including baicalein, and IS were detected

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